GMJ passes another milestone

Sugammadex: another milestone in clinical neuromuscular pharmacology.

Sugammadex is a revolutionary investigational reversal drug currently undergoing Phase III testing whose introduction into clinical practice may change the face of clinical neuromuscular pharmacology. A modified gamma-cyclodextrin, sugammadex exerts its effect by forming very tight water-soluble complexes at a 1:1 ratio with steroidal neuromuscular blocking drugs (rocuronium > vecuronium >> pan...

Another Milestone for Transcatheter Valve Therapy

The first mechanical heart valve prosthesis, designed by Dr Charles Hufnagel, was implanted to the descending aorta of a 30-year-old woman with severe aortic regurgitation in 1952.1 Eight years after the initial successful prosthetic valve implantation, Dr Harken sutured a prosthetic valve (Starr Edwards Valve) to the aortic annulus after removing the diseased native valve. During the ensuing y...

No best, only better: another APSTH milestone

It begins with the Sino-Japanese Symposium on Coagulation, Fibrinolysis, and Platelet first held in Hanchow, China in 1990, and again in Taipei, Taiwan in 1992. Thanks to the persistence and hard work of the conference founders and the participation of colleagues from countries around the world, that small, oligo-country conference has evolved into a regional conference now held every two years...

Valve in valve: another milestone for transcatheter valve therapy.

Editorial Valve in Valve Another Milestone for Transcatheter Valve Therapy

The first mechanical heart valve prosthesis, designed by Dr Charles Hufnagel, was implanted to the descending aorta of a 30-year-old woman with severe aortic regurgitation in 1952.1 Eight years after the initial successful prosthetic valve implantation, Dr Harken sutured a prosthetic valve (Starr Edwards Valve) to the aortic annulus after removing the diseased native valve. During the ensuing y...